Joint Global Health Trials scheme: people we've funded

2016

Dr Aneel Bhangu

University of Birmingham

Pilot: Development grant for a multi-centre, randomised trial to reduce surgical site infection following emergency gastrointestinal surgery

Professor Nathan Congdon

Queen's University Belfast

Pilot: Performance of EArly Retinal Laser (PEARL)

Professor Nicholas Day

University of Oxford

Assessing the safety of low-dose primaquine in plasmodium falciparum-infected African children with glucose 6 phosphate dehydrogenase deficiency 

Professor Brian Greenwood

London School of Hygiene and Tropical Medicine

A comparative trial of seasonal vaccination with the malaria vaccine RTS,S/AS01, seasonal malaria chemoprevention, and the two interventions combined

Dr Joseph Jarvis

London School of Hygiene and Tropical Medicine

High-dose AMBISOME on a fluconazole backbone for cryptococcal meningitis induction therapy in sub-Saharan Africa: a randomised controlled trial

Professor Feiko ter Kuile

Liverpool School of Tropical Medicine

Intermittent preventive treatment with DHA-piperaquine for malaria in pregnancy in areas with high sulphadoxine-pyrimethamine resistance in Africa

Professor Charles Newton

University of Oxford

Pilot: Parenteral interventions to support families of children with neurodisability in low-resource settings

Dr Martha Nwangome

KEMRI-Wellcome Trust Research Programme, Kenya

Pilot: Improved Breastfeeding support to treat Acute Malnutrition among Infants under six months (IBAMI)

Dr Pablo Perel

London School of Hygiene and Tropical Medicine

Pilot: InterTxt2Heart Pilot - a trial to evaluate efficacy of text messages to improve adherence to cardiovascular medications in secondary prevention

Professor Priscilla Reddy

Human Sciences Research Council, South Africa

Pilot: A study of improving outcomes in teenage pregnancy using a combined tailored M-Health program and motivational interviewing intervention

Dr Anna Roca

MRC Unit, The Gambia

Pre-delivery administration of azithromycin to prevent neonatal sepsis and death: a phase III double-blind randomised clinical trial

Professor Mark Rowland

London School of Hygiene and Tropical Medicine

Combination interventions for controlling malaria transmitted by pyrethroid-resistant mosquitoes: a novel bed net with synergist and IRS formulation

Professor Alan Stein

University of Oxford

Randomised control trial to evaluate an intervention for depressed HIV-positive women in the perinatal period, to enhance child development and reduce maternal depression

Professor Richard Velleman

Sangath Community Health NGO, Goa, India

Pilot: Bridging the mental health treatment gap through telepsychiatry – 'REACH' a formative research project from Goa, India

2015

Dr Steve Allen

Liverpool School of Tropical Medicine

Pilot: Exploratory observational study of therapeutic feeds used to treat intestinal inflammation in Malawian children with severe acute malnutrition (SAM)

Professor Simon Brooker and Dr Rachel Pullan

London School of Hygiene and Tropical Medicine

Interrupting transmission of soil-transmitted helminths: a cluster randomised trial evaluating alternative treatment strategies in Kenya

Dr Ed Clarke

MRC Unit, The Gambia

A randomised, observer-blind, non-inferiority trial to evaluate alternative human papillomavirus vaccination schedules in young females in West Africa

Professor Antonio Dans

McMaster University, Canada

A randomised controlled trial of influenza vaccine to prevent adverse vascular events

Professor Umberto D'Alessandro

MRC Unit, The Gambia

Reactive household-based self-administered treatment against residual malaria transmission: a cluster randomised trial

Dr Paramjit Gill

University of Birmingham

Pilot: Pakistan Prevention Programme for Gestational Diabetes Mellitus (PPP-GDM): a feasibility study

Dr Nusrat Husain

University of Manchester

Multi-centre randomised controlled trial to evaluate the clinical and cost-effectiveness of a culturally adapted therapy (C-MAP) in patients with a history of self-harm

Dr Amina Jindani

St George's University of London

A randomised trial to evaluate the toxicity and efficacy of 1200mg and 1800mg rifampicin daily for four months in the treatment of pulmonary tuberculosis

Dr Rupert Jones

Plymouth University

Pilot: A development study to examine feasibility and acceptability of pulmonary rehabilitation in Uganda for adults with chronic respiratory disease

Dr Mei Lin

Shandong University, China

Pilot: Develop an interventional study on reducing antibiotic over-prescribing among children with URIs in rural Guangxi, China

Professor Li Ling

Sun Yat-Sen University, China

Pilot: Development of tobacco control trial among migrant workers in Guangzhou, China

Dr Manu Mathur

Public Health Foundation of India

Pilot: Exploring the feasibility of school-based interventions to reduce sugar-sweetened beverage consumption in India

Dr J Jaime Miranda

Peruvian University Cayetano Heredia, Peru

Pilot: REDEEM trial – the effect of individual and mixed REwards in DiabEtEs Management; a randomised controlled trial

Dr Penelope Anne Phillips-Howard

Liverpool School of Tropical Medicine

Menstrual cups and unconditional cash transfer to reduce sexual and reproductive harm and school drop-out in adolescent schoolgirls in western Kenya

Dr Kamran Siddiqi

University of York

Pilot: Children Learning About Second-hand Smoke (CLASS II) - a pilot cluster randomised controlled trial

Dr Alan Smyth

University of Nottingham

Pilot: A feasibility and pilot study of the effects of Rojiroti microfinance on the health and nutrition of children under five in Bihar, northern India

Professor Tazneen Jafar

National University of Singapore

Primary care strategies to reduce high blood pressure: a cluster randomised trial in rural Bangladesh, Pakistan and Sri Lanka

Dr Andrew Vallely

Papua New Guinea Institute of Medical Research

Point-of-care testing and treatment of sexually transmitted infections to improve pregnancy outcomes in resource-limited, high-burden settings

Dr Deborah Watson-Jones

London School of Hygiene and Tropical Medicine

A dose reduction immunobridging and safety study of two HPV vaccines in Tanzanian girls

2014

Dr Helen Baker-Henningham

Bangor University

The 'Irie Classrooms Toolbox': a cluster randomised trial of a universal violence prevention programme in Jamaican preschools

Professor James Jay Berkley

University of Oxford

First Line Antimicrobials in Complicated Severe Acute Malnutrition: FLACSAM

Dr Ed Clarke

MRC Unit, The Gambia

A randomised controlled trial to evaluate the effect of maternal or neonatal pneumococcal conjugate vaccination on pneumococcal carriage in early life

Professor Lelia Duley

University of Nottingham

Pilot cord trial: Feasibility of conducting a trial evaluating timing of cord clamping for preterms in low- and middle-income countries

Professor Anneke Hesseling

Stellenbosch University, South Africa

A phase III cluster randomised placebo-controlled trial to assess the efficacy of preventive therapy in child and adolescent contacts of MDR-TB

Dr Tanvir Mahmudul Huda

ICDDRB, Bangladesh

Pilot: Is Lactoferrin more effective than inorganic iron in treating and preventing iron deficiency anaemia in non-pregnant women and pregnant women? Two randomised trials.

Professor Stephen Lawn and Dr Katherine Fielding

London School of Hygiene and Tropical Medicine

Rapid Urine-Based Screening for Tuberculosis to Reduce AIDS-Related Mortality in Hospitalized Patients in Africa (STAMP) Trial

Professor Steven Lindsay

Durham University

Can improved housing provide additional protection against clinical malaria over current best practice? A household-randomised controlled trial

Dr David Meya

Makerere University, Uganda

Adjunctive Sertraline for the treatment of HIV-associated cryptococcal meningitis

Professor David Moore

London School of Hygiene and Tropical Medicine

Pilot: Streamlined TB diagnosis and treatment

Professor Landon Myer

University of Cape Town, South Africa

Postpartum adherence clubs for antiretroviral therapy: a randomised controlled trial

Professor Kazem Rahimi

University of Oxford

A trial of low-cost, technology-assisted, integrated care delivery programme to prevent serious cardiovascular events in disadvantaged populations

Professor Ian Roberts

London School of Hygiene and Tropical Medicine

CRASH-3 trial: Tranexamic acid for the treatment of significant traumatic brain injury: an international randomised, double-blind placebo controlled trial

Professor Janneke van de Wijgert

University of Liverpool

Pilot: Preparing for a clinical trial of interventions to maintain normal vaginal microbiota for preventing adverse reproductive health outcomes in Africa

Professor Andrew Weeks

University of Liverpool

BabyGel pilot: a study of a cluster randomised trial of the provision of alcohol handgel to postpartum mothers to prevent neonatal infective morbidity in the home

Professor Denis Xavier

St John's National Academy of Health Science, India

Pilot: Policy and peer mentor intervention programmes on cardiovascular disease at small- to medium-sized worksites in three South Asian countries

2013

Professor Diana Gibb

Medical Research Council

A randomised trial of therapy shortening for minimal tuberculosis with new WHO-recommended doses and FDC drugs in African/Indian HIV+/HIV- children

Professor Mark W Rowland

London School of Hygiene and Tropical Medicine

Combination interventions for controlling malaria transmitted by pyrethroid resistant mosquitoes: a novel bed net with synergist and IRS formulation

Dr Hector Garcia

Universidad Peruana Cayetano Heredia, Peru

Pilot Study - a case for free supply of anti-epileptic drugs in resource-poor regions

Professor Kathryn Maitland

Imperial College London

MICA: children's oxygen administration strategies trial

Dr Patrick Phillips

MRC Clinical Trials Unit at University College London

Two-month Regimens Using Novel Combinations to Augment Treatment Effectiveness for drug-sensitive Tuberculosis: the ‘TRUNCATE-TB’ trial

Dr Immo Kleinschmidt

London School of Hygiene and Tropical Medicine

From malaria control to sustainable elimination: cluster randomised trial comparing targeted versus generalised vector control in South Africa

Dr Karen M Devries

London School of Hygiene and Tropical Medicine

The Good Schools Study: a cluster randomised controlled trial of an intervention to prevent violence against children in Ugandan primary schools

Dr Anatoli Kamali

MRC/UVRI Uganda Research Unit on AIDS, Uganda

Pilot Study - uptake and impact of HIV combination (HIVCOMB) interventions on HIV incidence among fishing communities in Uganda

Dr Anita Zaidi

Aga Khan University, Pakistan

A double blind randomised community-based trial of amoxicillin versus placebo for non-severe pneumonia in children aged 2-59 months in Pakistan

Professor Tazeen Jafar

Aga Khan University, Pakistan and National University of Singapore, Singapore

Pilot Study - integrated primary care strategies to reduce high blood pressure: a cluster randomised trial in rural Pakistan and Sri Lanka

2012

Professor Richard Price

University of Oxford

Improving the radical cure of vivax malaria: a multicentre randomised comparison of short and long course primaquine regimens

Dr Audrey Prost

University College London

Community intervention to improve growth among children under two in rural India

Arri Coomarasamy

University of Birmingham

Effectiveness of antibiotic prophylaxis during surgical evacuation of the uterus for miscarriage management in low-income countries (AMS trial)

Professor Umberto D'Alessandro

MRC Unit, The Gambia

Primaquine's gametocytocidal efficacy in malaria asymptomatic carriers treated with dihydroartemisinin-piperaquine

Dr Gail Davey

University of Sussex

Randomised controlled trial of podoconiosis treatment in northern Ethiopia

Dr Carlton Evans

Imperial College London

Community randomised evaluation of socioeconomic intervention to prevent TB

Professor Graham Foster

Queen Mary, University of London

Step-down affordable treatment for chronic hepatitis B infection in Africa and India Acronym - STEP-HEP

Professor Stephen Gordon

Liverpool School of Tropical Medicine

An advanced cookstove intervention to prevent pneumonia in children under five years old in Malawi: a cluster randomised controlled trial

Professor Oye Gureje

University of Ibadan, Nigeria

A cluster randomised controlled trial of a STEPped CARE intervention for depression in primary care

Dr Sarah Staedke

London School of Hygiene and Tropical Medicine

School-based treatment with ACT to reduce transmission; evaluation of the community impact of intermittent preventive treatment for malaria in Uganda

Dr Ambrose Talisuna

University of Oxford

Efficacy of mobile phone short message service (SMS) on malaria treatment adherence and post-treatment review

Professor Sir Brian Greenwood

London School of Hygiene and Tropical Medicine

A trial of the benefit of including azithromycin in the drug combination used for seasonal malaria chemoprevention in African children

2011

Dr Somphou Sayasone

Swiss Tropical and Health Institute, Switzerland

Tribendimidine for the treatment of liver fluke infection in South-east Asia

Professor Diana Gibb

Medical Research Council

Reduction of Early mortaLITY in HIV-infected African adults and children starting antiretroviral therapy: REALITY trial

Dr Jeremy Day

University of Oxford Clinical Research Unit, Vietnam

A clinical trial of dexamethasone to reduce mortality in cryptococcal meningitis

Dr Badara Cisse

London School of Hygiene and Tropical Medicine

Randomised trial of spatially targeted control to virtually eliminate malaria in areas of very low incidence and patchy transmission in Senegal

Dr Penelope A Phillips-Howard

Liverpool John Moores University

The effectiveness of Mooncups to reduce school absenteeism, and sexual and reproductive harms in Kenyan schoolgirls

Dr Thuy Le

University of Oxford

A randomised, open-label, comparative study of Itraconazole vs Amphotericin B for the induction therapy of Penicilliosis

Dr Alison Grant

London School of Hygiene and Tropical Medicine

TB fast track: effect of a point-of-care TB test-and-treat algorithm on early mortality in people with HIV accessing ART

Professor Feiko ter Kuile

Liverpool School of Tropical Medicine

Intermittent screening and treatment or intermittent preventive therapy for control of malaria in pregnancy in Indonesia

Dr Mark Hatherill

University of Cape Town, South Africa

MVA85A Tuberculosis vaccine prime and selective delayed BCG boost in infants of HIV-infected mothers

Dr Andrew Weeks

University of Liverpool

Induction of labour in pre-eclamptic women: a randomised trial comparing balloon catheter with oral misoprostol

People we've funded

Many of our grantholders carry out research in Africa and Asia. See our directories: