The inflammatory response as a targetable pharmacodynamic parameter of antileishmanial drugs

Maria Adelaida is a microbiologist and the coordinator of the Molecular Biology and Biochemistry Unit at CIDEIM. During her Fellowship she will investigate how immunological factors and antimicrobial drug concentrations interact to drive the therapeutic outcome in patients with cutaneous leishmaniasis. She will explore how inflammation can be exploited as a targetable pharmacodynamic parameter of anti-leishmanial drugs. Her project aims to provide the knowledge base for the design of novel therapeutic schemes that concomitantly optimise antimicrobial and immunological functions for improved efficacy of treatment, and to reduce exposure of patients to toxic systemic drugs.

This grant was awarded under the scheme's previous name of Intermediate Fellowships in Public Health and Tropical Medicine.