Studies of immunopathogenesis in dengue virus infection

Grantholders

  • Prof Gavin Screaton

    Imperial College London

Project summary

Professor Screaton will analyse several aspects of the immunology of dengue virus infection, a serious emerging tropical disease. Previous exposure to dengue virus can mean that an individual becomes more unwell when they encounter the virus on a second occasion. To allow better vaccine design and monitoring, there is a need for greater clarity about which components of the immune response are protective and which are damaging to the host.