Metabolic and hormonal regulation of pancreatic hormone secretion

Professor Rorsman will investigate how islet cells in the human pancreas function in health and disease by understanding the mechanisms that control the secretion of hormones, particularly insulin. Specifically, he plans to show how islet cells respond to the availability of nutrients and examine the crosstalk between the islets and the rest of the body. Professor Rorsman hopes that the knowledge gained will aid in the design of new drug treatments for diabetes.