Intrahost dynamics in treated and untreated malaria patients

Grantholders

  • Dr Standwell Nkhoma

    University of Malawi

Project summary

Standwell is a molecular biologist based at the Malawi-Liverpool-Wellcome Trust Clinical Research Programme. His Fellowship project aims to study the biology of multiple-genotype malaria infections from an area of high disease burden in Malawi. Multiple-genotype infections are extremely common in Africa, and present enormous challenges for both malaria research and control. Standwell will undertake a detailed characterisation of these complex infections using novel single-cell genomics approaches to better understand their genetic composition and to evaluate the relationship between within-host parasite diversity and malaria disease severity.

This grant was awarded under the scheme's previous name of Intermediate Fellowships in Public Health and Tropical Medicine.