Hungry for knowledge: elucidating the role of liver Kupffer cells in instructing the immune response against fed and intestinally derived antigens

Charlotte's research will focus on understanding the role played by liver-resident macrophages, Kupffer cells (KCs), in the regulation of systemic immune responses to antigens derived from the intestine. During her fellowship, she will work at Ghent University, Belgium, in collaboration with Dr Martin Guilliams and Professor Bart Lambrecht before moving to the University of Glasgow and collaborating with Dr Simon Milling. During her Fellowship, Charlotte hopes to further understand the outcomes of intestinally derived antigen recognition by KCs and the mechanisms behind these events.