Hadamard time-resolved crystallography: investigating fast structural dynamics using synchrotron radiation

Grantholders

  • Dr Briony Yorke

    University of Bath

Project summary

Briony's research focuses on developing new methods to investigate the molecular dynamics that are essential to biological processes. During her fellowship she will use a novel method for time-resolved crystallography to investigate the mechanism of UV damage in γD-crystallin, a process that eventually leads to the formation of cataracts. She will work with Professor Paul Raithby (University of Bath) to implement the new method at Diamond Light Source. Briony will collaborate with Professor Elspeth Garman (University of Oxford) to model radiation damage processes and Professor Arwen Pearson (Universität Hamburg) to investigate structural changes in γD-crystallin.