Impact of Vaccines on Antimicrobial Resistance
This scheme supports researchers investigating the impact of vaccines on antibiotic use and/or antimicrobial resistance. The aim is to support and inform vaccine decision-makers around the world and tackle antimicrobial resistance.
Scheme at a glance
For researchers with a PhD or the equivalent, and significant postdoctoral research experience.
Where your host organisation is based:
- Anywhere in the world
Type of researcher:
You're not a clinically qualified researcher.
- Public health
Level of funding:
Small awards are up to £250,000. Large awards are £250,000 to £750,000.
Duration of funding:
Flexible, depending on level of funding
Who can apply
You can apply for this award if you’re a researcher who wants to better understand the impact of vaccines on the use of antibiotics and the development of antimicrobial resistance (AMR). You must propose to analyse AMR data related to vaccine use that can be used by vaccine decision-makers.
The awards are open to individuals or teams of up to seven people from anywhere in the world.
You can apply if you’re based at:
- an academic research organisation
- a not-for-profit or government body
- a private sector organisation.
You must be able to accept our standard grant conditions.
Teams may be based in the same or in different organisations.
Each applicant should have a permanent, open-ended or long-term rolling contract, or the guarantee of one. Your salary must be paid by your host organisation.
If you hold a permanent, open-ended or long-term rolling contract but have to get your salary from external grant funding, you can ask us for this in your application. Your host organisation must confirm details about your employment contract.
Your research programme
Your programme must aim to analyse data on AMR or antibiotic use in the context of a human vaccine study.
You can either:
- analyse existing AMR data related to vaccine use
- collect and analyse new AMR data from an ongoing or planned vaccine study that has already been funded by Wellcome or elsewhere.
Types of AMR data that you may want to analyse include (but are not limited to):
- antibiotic use
- drug-resistant infections
- antibiotic prescribing behaviour
- antibiotic seeking behaviour
- health and economic costs.
Examples of completed, ongoing or planned vaccine studies include (but are not limited to):
- randomised controlled trials
- observational studies: time series, comparative cohorts, case series or case-control studies.
You can propose to work on vaccines that are marketed or in development. The vaccines should target pathogens that:
- are becoming more difficult to treat with antibiotics
- cause symptoms that drive antibiotic use.
These may include (but are not limited to) vaccines against:
- S. pneumoniae
- H. influenzae
- S. Typhi
We will assess:
- the scope and feasibility of your proposal
- how the study will strengthen understanding of the impact of vaccines on the use of antibiotics and the development of AMR
- whether the proposal will produce meaningful data that will be used by vaccine decision-makers
- the track records of all team members, relative to their career stage
- your plans for managing any risks related to the study.
There are two levels of funding you can apply for:
- small awards up to £250,000
- large awards between £250,000 and £750,000.
Your costs should be justifiable and appropriate for your proposed activities.
You can request support for:
- basic salary
- employer’s contributions, including any statutory obligations (eg National Insurance contributions if you’re based in the UK) and pension scheme costs
- Apprentice Levy charges for UK-based salaries
- any incremental progression up the salary scale
- locally recognised allowances such as London allowance.
Staff salaries should be appropriate to skills, responsibilities and expertise. You should ask your host organisation to use their salary scales to calculate these costs, which should include:
You should allow for salary pay awards during Year 1. These should be based on pay awards already agreed: if you don’t know what the pay award is yet then use our inflation rate.
From Year 2 onwards, you should use your organisation’s current pay rates. We’ll provide a separate inflation allowance for salary inflation costs.
Find out more about people working on a Wellcome grant.
We may make a contribution towards the salary of departmental technicians funded by Research England and its equivalents in Scotland, Wales and Northern Ireland. You will need to provide a full audit record of their time on your project.
- visa costs for the researcher’s partner and dependent children
- essential associated costs, such as travel to attend appointments at a visa application centre or embassy if you can justify these
- Immigration Health Surcharge costs for the researcher, their partner and dependent children if they will be in the UK for six months or more.
- are European Union citizens living in the UK
- meet the requirements for settled status set by the UK government.
We will cover the salary costs of all staff, full or part time, who will work on your project. Staff members may include research assistants, technicians, fieldworkers or clinical staff employed on your grant.
We don’t usually provide a salary for any applicants for this scheme.
We don't provide studentship stipends.
Visa, work permit and settled status costs
If you have named researchers on your grant whose salaries will be funded by Wellcome, you can ask for visa or work permit costs to help them take up their posts at the host organisation. You can also ask for:
You can also ask for settled status costs if the named researchers:
You can also include these costs for the researcher’s partner and dependants.
We will pay for the materials and consumables you need to carry out your proposed research, including:
- laboratory chemicals and materials (eg reagents, isotopes, peptides, enzymes, antibodies, gases, proteins, cell/tissue/bacterial culture, plasticware and glassware)
- associated charges for shipping, delivery and freight.
You can ask for smaller items of equipment that are essential to your proposed research project. Costs may include purchase, delivery, installation, maintenance and training, where necessary.
If you want to request larger items, please contact us before applying.
We will cover VAT and import duties if:
- the usual UK exemptions on equipment used for medical research don’t apply
- you’re applying from a non-UK organisation, and you can show these costs can’t be recovered.
We will cover maintenance costs for equipment if:
- you are requesting it in your application
- it is existing equipment that is:
- funded by us or another source
- essential to the proposed research project
- more than five years old
- cost effective to keep maintaining it.
We won’t cover maintenance costs for equipment if there is a mechanism in place to recoup these costs through access charges.
We will cover the cost of one personal computer or laptop per person up to £1,500.
We won't pay for:
- more expensive items, unless you can justify them
- installation or training costs.
You can ask for the cost of access to shared equipment or facilities if they’re essential to your research project. These may include materials and consumables, plus a proportion of:
- maintenance and service contracts
- staff time costs for dedicated technical staff employed to operate the equipment or facility.
We don’t cover the costs of:
- estates and utilities
- depreciation or insurance
- other staff eg contributions towards departmental technical, administrative and management staff time.
If the facilities or equipment were paid for by a Wellcome grant, you can only ask for access charges if:
- the grant has ended
- any support for running costs and maintenance contracts has ended.
We cover research management and support costs if:
- your host organisation is in a low- or middle-income country and your grant will be directly awarded to that organisation,
- part of your grant will be sub-contracted to an organisation in a low- or middle-income country.
We don't cover these costs if your host organisation will include the sub-contracted funding in its annual report to the UK Charity Research Support Fund.
They can include:
- training costs, eg transferable skills and personal development training for you and any other people employed on your grant
- costs for short-term professional training for administrative, technical and support staff
- administration, eg grant management, technical and administrative services
- other costs which are necessary for your research, eg computing and internet access costs, access to electronic resources, facility and running costs such as utilities, furniture, waste disposal and incineration, and building maintenance.
The total research management and support costs should not be more than 20% of the direct research costs you're requesting.
See a list of low- and middle-income countries.
How to apply for these costs
- give a full breakdown of costs in your grant application form (you can't ask for a percentage of the research costs)
- explain why these costs are necessary for your research
- include a letter from the finance director of your host organisation with your application, confirming that the breakdown is a true representation of the costs incurred.
- All applicants named on your grant – £2,000 a year
- Staff employed on your grant – £1,000 each a year
- Wellcome is paying your salary
- the conference is directly related to your research
- the caring costs are over and above what you'd normally pay for care
- the conference organiser and your employing organisation are unable to cover the costs.
You should use the most suitable and economical form of travel. Please include a breakdown for each part of your trip, eg air fares and number of journeys.
You can ask for travel and subsistence costs for collaborative visits for you and any research staff employed on your grant. You’ll need to justify each visit and its duration.
You can ask for a contribution towards the costs of attending scientific and academic meetings and conferences, including registration fees. The limits are:
You’ll need to specify the amount you’re requesting for each person.
You can also ask for costs to cover caring responsibilities if you or any staff employed on your grant attend a conference. This includes childcare and any other caring responsibility you have, provided:
You can ask for up to £1,000 per person for each conference.
We will pay for other essential visits, eg to facilities, for sample collection and for fieldwork. You can include subsistence costs.
If you’re away for up to one month you can ask for subsistence costs. These include accommodation, meals and incidentals (eg refreshments or newspapers).
If your administering organisation has a subsistence policy, use their rates.
If your administering organisation doesn’t have a subsistence policy, please use the HMRC rates.
If you’re away for more than one month and up to 12 months, we will pay reasonable rental costs only, including aparthotels. You should discuss appropriate rates with your administering and host organisations, or Wellcome, as appropriate. We expect you to choose the most economical options, booked in advance where possible.
If you’re from a low- or middle- income country and will be working in a high-income country for more than one month and up to 12 months, you can also ask for up to £20 a day to cover extra costs, such as transport and incidentals.
If you’re away for more than 12 months, we will pay the costs of your housing. You should discuss your needs with your administering and host organisations.
The allowance we provide will be based on family and business need. We will set the maximum allowance we pay for each location. This will be based on current market data or, where data is unavailable, in consultation with your administering organisation, using equivalent market rates. Please contact us if you need help calculating the costs.
We will cover the direct expenses you have to pay to find and rent a home. We will not cover the cost of utilities or any refurbishment.
If you or any research staff employed on your grant will be doing research away from your home laboratory, we'll help with the additional costs of working on the project overseas. Please see the 'Overseas allowances' section for details.
We cover fieldwork costs if they’re essential and you can justify them. Costs can include:
- survey and data collection, including communication and data collection services and any associated costs such as essential field materials, travel costs and language translation services
- the purchase, hire and running costs of vehicles dedicated to your project
- expenses for subjects and volunteers, including the recruitment of participants, their participatory fees and travel costs
- statistical analysis.
You can ask for other fieldwork costs that aren’t listed here, but you’ll need to justify them.
If your organisation receives block funding through the UK’s Charity Open Access Fund (COAF) you can ask them to cover your open access article processing charges.
If you're at an organisation that doesn't receive COAF funding, we’ll supplement your grant when your paper has been accepted for publication.
You can't ask for these charges in your grant application.
Costs you may ask for (you will have to justify these costs in your application):
- specialist publications that are relevant to the research and not available in institutional libraries
- consultancy fees
- expenses for subjects and volunteers – includes recruitment of participants, their participatory fees and travel, as well as interviewee expenses
- reasonable research-associated costs related to the feedback of health-related findings but not any healthcare-associated costs
- costs associated with developing an outputs management plan
- questionnaires, recruitment material, newsletters etc for clinical, epidemiological and qualitative research studies
- public engagement materials where dissemination (including printing and publishing) is a key activity of the project
- recruitment, advertising and interviewee travel costs for staff to be employed on the grant
- formal transferable skills and personal development training, including the International Funders Award
- purchase, hire and running costs of project-dedicated vehicles.
Costs we won’t pay:
- estates costs – such as building and premises costs, basic services and utilities. This also includes phone, postage, photocopying and stationery, unless you can justify these within a clinical or epidemiological study.*
- research, technical and administrative staff whose time is shared across several projects and isn’t supported by an audit record*
- PhD stipends
- charge-out costs for major facilities* – departmental technical and administrative services, and use of existing equipment
- cleaning, waste and other disposal costs*
*We will fund these costs in the case of animal-related research.
- indirect costs – this includes general administration costs such as personnel, finance, library, room hire and some departmental services
- office furniture, such as chairs, desks, filing cabinets, etc.
- clothing such as lab coats, shoes, gloves, protective clothing
- non-research related activities, eg catering, room and venue hire for staff parties, team-building events and social activities
- indemnity insurance (insurance cover against claims made by subjects or patients associated with a research programme)
- ethics reviews, unless you are in a low- or middle-income country
- radiation protection costs.
Costs grantholders can claim on biomedical science research grants.
You can also apply for Research Enrichment funding to increase the impact of your work through activities in public engagement, open research, and diversity and inclusion.
What we don’t offer
We don't fund:
- salary costs for any applicants (these must be provided by their organisation).
- costs for capital build or refurbishment.
We don't fund overheads unless they're included on this page (for example research management and support costs).
You must submit your application through the Wellcome Trust Grant Tracker (WTGT).Start your application
Stages of application
Email an expression of interest to us
You must send your expression of interest to us no later than 17:00 BST on Friday 6 September 2019. Email firstname.lastname@example.org with the following details:
- a brief outline of your proposal (500 words maximum), including information about team members and collaborators
- whether your proposal will involve collecting new data or using an existing dataset.
We'll contact you within two workings days of receiving your email. If suitable, we'll invite you to submit an application.
Submit your invited application
You must submit your application through Grant Tracker.
If you're applying as a team, the lead applicant must submit the application form on behalf of the team.
We will only accept one application from each lead applicant, co-applicants can be included in more than one application.
‘Details of proposal’ section
In the ‘Details of proposal’ section, provide the following information in no more than 3,000 words:
- a brief description of the completed, ongoing or planned vaccine study, including geographic location, target populations, size and vaccine
- the data you will analyse as part of your proposal
- the type of analysis you will carry out
- how your analysis could guide policy makers in their decisions about using existing vaccines and/or developing new vaccines to combat AMR.
If your proposal involves collecting new data from an ongoing or planned study, please tell us who the study is funded by and the start and end dates.
Assessment of your full application
Applications will be assessed by the Vaccines Advisory Panel, and Wellcome staff.
We aim to give you a funding decision by November 2019. There are no interviews, but we may contact you for more information about your proposal.
In general, we don't provide specific written feedback to unsuccessful applicants.
If you are disabled or have a chronic health condition, we can support you with the application process.
You must submit your application by 17:00 (BST) on the deadline day. We don’t accept late applications.
Expressions of interest submitted by email
6 September 2019, 17:00 BST
Invited full applications deadline
12 September 2019, 17:00 BST
This is a one-off scheme.
Expressions of interest submitted by email
6 September 2019, 17:00 BST
Invited full applications deadline
12 September 2019, 17:00 BST